정신장애환자의 혈청 면역글로부린의 변동

• 영문명: Changes o f Serum Immunoglobulins in Psychiatric Patients
• 발행기관: 대한신경정신의학회
• 저자명: 최영태 오동원
• 간행물 정보: 『신경정신의학』제29권 제5호, 1000~1007쪽, 전체 8쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 1990.09.30

영문 초록

Immunoglobulins, IgG, IgA, IgM, and IgE were quantified in serum from 15 schizophrenics, 13 neurotics and 20 healthy volunteers using single radial immunodiffusion and radioimmunoassay techniques. The serum immunoglobulins of patients were measured first on admission and secondly when symptoms were improved. The findings were as follows * 1) No difference of each immunoglobulin level was noticed between schizophrenics and normal controls, but IgG level of the female neurotics was significantly lower than that of the female normal controls. 2) Among the schizophrenic subjects, age of onset, sex, and dosage of antipsychotic medication had no influence on the immune function. 3) There was no significant difference of each Ig level in schizophrenics and neurotics upon clinical improvement. In conclusion, it is suggested that there is no alteration immune system of schizophrenia. Also, it is suggested that there is possibility of immune dysfunction in female neurotics.

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