아메드밸브 삽입술 후 전방 내 실리콘관 첨단의 위치와 각막내피세포 변화

• 영문명: Location of the Tube Tip in the Anterior Chamber and Change in Corneal Endothelium after Ahmed Valve Implantation
• 발행기관: 대한안과학회
• 저자명: 오원혁 김태우 박기호 김동명 ,Won Hyuk Oh, MD, Tae Woo Kim, MD, PhD,, Ki Ho Park, MD, PhD,, Dong Myung Kim, MD, PhD,
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume54,number3, 469~474쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2013.03.15

영문 초록

Purpose: To evaluate the impact of location of a silicone tube tip in the anterior chamber on corneal endothelium after Ahmed glaucoma valve implantation. Methods: We measured the distance from the tip of a silicone tube in the anterior chamber to the posterior surface of the cornea by anterior segment optical coherence tomography (OCT) in 24 eyes of 21 patients who underwent Ahmed glaucoma valve implantation. All surgeries were performed by a single surgeon. The corneal endothelial cells of central, superior, superotemporal, and superonasal area of the cornea were examined by specular microscope before and after surgery. Results: The distance from the tip of the silicone tube in the anterior chamber to the posterior surface of the cornea and the corneal endothelium were measured at 19.2 ± 11.8 months (2.8-41.2 months) after surgery. At the central corneal area, a statistically significant decrease in the number of corneal endothelial cells (2278 ± 565/mm2 vs. 2177 ± 529/mm2, p = 0.043) after surgery was observed, but no relationship was found between the amount of decrease and distance from the tip to the posterior surface of the cornea. At the superotemporal corneal area where the tip of the silicone tube was located in the anterior chamber, there was more significant loss of corneal endothelial cells than in the other areas after surgery (p = 0.006). Moreover, the amount of endothelial cell loss at the superotemporal area was negatively correlated to the distance from the tip to the posterior surface of the cornea (partial correlation coefficient by time -0.558, p = 0.031). Conclusions: To minimize the loss of corneal endothelial cells after Ahmed glaucoma valve implantation, ensuring a sufficient distance from the tip of the silicone tube to the posterior surface of the cornea is important.

키워드

Ahmed glaucoma valve, Anterior segment optical coherence tomography, Corneal endothelial cell