당뇨 환자에서 비스테로이드 항염증제 점안이 백내장 수술 후 황반부종 발생에 미치는 효과

• 영문명: Effect of Non-Steroidal Anti-Inflammatory Drugs on Cystoid Macular Edema in Diabetic Patients after Cataract Surgery
• 발행기관: 대한안과학회
• 저자명: 고창현 정성근,Chang Hyun Koh, MD, Sung Kun Chung, MD, PhD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume54,number3, 427~431쪽, 전체 5쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2013.03.15

영문 초록

Purpose: The present study analyzed the effect of non-steroidal anti-inflammatory drugs (NSAIDs) on cystoid macular edema in diabetic patients after cataract surgery. Methods: Among 105 eyes of 84 diabetic patients, 43 patients who were administered Pranopulin? (JW pharmaceutical, Korea) starting 3 days before surgery comprised the experimental group. The control group included 41 patients who were not given Pranopulin?. The results consisted of macular thickness measurements and total macular volume which were quantified by optical coherence tomography (OCT, Carl Zeiss Meditec). Results: Macular thickness of the experimental group was 7.72 ± 13.04 μm at postoperative 1 month, 7.15 ± 13.62 μm at postoperative 2 months and was significantly thinner than in the control group (p < 0.05). Macular volume of the experimental group was 0.33 ± 0.49 mm3 at postoperative 1 month, 0.31 ± 0.43 mm3 at postoperative 2 months and was also significantly smaller than in the control group (p < 0.05). Conclusions: Using NSAIDs prophylactically before cataract surgery can effectively reduce the risk of postoperative cystoid macular edema in diabetic patients.

키워드

Cystoid macular edema, Nonsteroidal anti-inflammatory drug, Phacoemulsification