고등각막표면연마굴절수술 후 각막지각, 눈물막 및 안구표면의 변화

• 영문명: Changes in Corneal Sensation, Tear Film Stability and Ocular Surface after Advanced Surface Ablation
• 발행기관: 대한안과학회
• 저자명: 이병희 김은주 김지현 이광자 이규원 박영정,Byeong Hee Lee, MD, Eun Joo Kim, MD, Jee Hyun Kim, MD, Gwang Ja Lee, MD,Kyoo Won Lee, MD, PhD, Young Jeung Park, MD, PhD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume54,number3, 408~415쪽, 전체 8쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2013.03.15

영문 초록

Purpose: To evaluate the changes in tearfilm, corneal sensation and ocular surface after advanced surface ablation. Methods: Tearfilm break-up time (BUT), Schirmer test without local anesthesia, fluorescein staining, corneal sensitivity test, ocular surface disease index (OSDI), and conjunctival impression cytology were evaluated in 50 eyes of 25 patients who underwent advanced surface ablation preoperatively and postoperatively at 2 weeks and at 1, 2, 3, and 6 months. Each value was compared to the preoperative value. Results: OSDI diminished by 2 weeks postoperatively, and corneal sensation diminished by 1 month postoperatively (p < 0.05). There were significant decreases in BUT by 2 weeks to 1 month postoperatively as well as decreases in the Schirmer test by 2 to 3 months postoperatively (p < 0.05). Fluorescein staining increased at 2 weeks postoperatively (p < 0.05). Goblet cells decreased substantially by 1 month postoperatively and conjunctival squamous metaplasia increased significantly by 2 months postoperatively (p < 0.05). Conclusions: Advanced surface ablation may affect tearfilm, corneal sensation and ocular surface up to 3 months postoperatively. Early treatment of dry eye syndrome following advanced surface ablation should strongly be considered.

키워드

Advanced surface ablation, Dry eye, Impression cytology