지실의 생리활성성분

• 영문명: Biological Active Components of Fruits of Poncirus trifoliata
• 발행기관: 대한약학회
• 저자명: 윤황금(Whang Geum Youn) 김동현(Dong Hyun Kim) 김남재(Nam Jae Kim) 홍남두(Nam Doo Hong)
• 간행물 정보: 『약학회지』제36권 제6호 (1992년), 548~555쪽, 전체 8쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1992.12.29

영문 초록

The biological activities of fruits of Poncirus trifoliata have been studied. 70% Ethanol extract of Ponciri Fructus was fractionated with ether, ethyl acetate and n-butanol by turns. The ether fraction showed antibacterial activity on Staphylococcus aureus and inhibited the contractability of the isolated mice ileum. The ethyl acetate and n-butanol fractions showed the anti-edematous effect on the carrageenin-induced edema of rat hindpaw. From the n-butanol fraction, one of the flavonoid glycoside was isolated and identified as poncirin. Ponciri Fructus contained about 6% poncirin which was 5,7-dihydroxy-4''-methoxy flavanone rhamnoglucoside and poncirin showed antiinflammatory activities. Poncirin was considered as the major effective component of Ponciri Fructus.

키워드

Poncirus trifoliata antiinflammatory effect flavonoid glycoside poncirin.