정신분열증환자의 혈청 NK 세포활성도에 관한 연구

• 영문명: A Study of Natural Killer Cell Activity in Schizophrenia
• 발행기관: 대한신경정신의학회
• 저자명: 박중조 은헌정 김임
• 간행물 정보: 『신경정신의학』제34권 제2호, 419~426쪽, 전체 8쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 1995.03.30

영문 초록

The purpose of this study was to com pare N K cell activity in schizophrenic patients with those in norm al healthy subjects. 53 schizophrenic patients and 49 healthy subjects were included in the study. Of 53 schizophrenic patients, 42 patients h ad been treated with antipsychotic drugs for at least 6 months before the study and 11 patients had been drug free before the study. The results of the study were as follows : 1) Schizophrenic patients showed significantly lower NK cell activity than control subjects did. There was a statistically significant difference between schizophrenic patients and control subjects in N K cell activity(p<0.0001). 2) There was a statistically significant difference in NK cell activity between drug treated group and drug free group(p<0.000l). 3) There was not a statistically significant difference in NK cell activity between drug free group and normal control group (p〉0.05). 4) Sex difference of the N K cell activity was not statistically significant(p〉0.05). 5) Age difference of the N K cell activity was not statistically significant(p>0.05). In conclusion, these findings suggest that NK cell activity is significantly associated with schizophrenia.

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키워드

Schizophrenia NK cell activity