Effects of Oil type on the Stability of Oil-in-Water Lipid Nanoemulsion

• 발행기관: 한국응용과학기술학회 (구.한국유화학회)
• 저자명: Seung-Jun Lee Sa Ra Han Jae Hyun Jeong Jong-Duk Kim
• 간행물 정보: 『한국응용과학기술학회지』한국유화학회지 제33권 제4호, 667~675쪽, 전체 9쪽
• 주제분류: 공학 > 화학공학
• 파일형태: PDF
• 발행일자: 2016.12.30

영문 초록

Nanoemulsions are actively used in several applications for pharmaceutical, cosmetic and chemical industries. In this study, we propose the use of microfluidizer known as high pressure homogenizer to prepare lipid nanoemulsion as a potent cosmetic delivery carrier. The lipid nanoemulsions were prepared by O/W emulsion with hydrogenated lecithin and different type of oils. Effects of oil type on the stability of the lipid nanoemulsion were investigated with Dynamic Light Scattering (DLS) and Zeta-potential. Arbutin was used as model drug for transdermal administration through hairless mouse skin. Transdermal arbutin delivery using the lipid nanoemulsions was studied with HPLC method.

목차

1. Introduction

2. Experimental

3. Results and Discussion

4. Conclusions

References

키워드

Lipid Nanoemulsion Microfluidizer Transdermal delivery Arbutin