한국형 우울장애 약물치료 알고리듬 2025 (III): 소아·청소년

• 영문명: Korean Medication Algorithm Project for Depressive Disorder 2025 (III): Child and Adolescent
• 발행기관: 대한신경정신의학회
• 저자명: 양찬모 심세훈 박원명 서정석 김낙영 최원석 우영섭 박성용 김원 이정구 성형모 왕성민 정영은 정종현 민경준 김문두 윤보현
• 간행물 정보: 『신경정신의학』제64권 제3호, 200~212쪽, 전체 13쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2025.08.31

국문 초록

Objectives The Korean Medication Algorithm Project for Depressive Disorder 2025 (KMAP-DD 2025) represents a revision of the prior iterations. The primary objective of the present study was to refine treatment guidelines for major depressive disorders (MDDs) in child and adolescent populations. Methods The survey instrument comprised 21 questionnaires specifically tailored for children and adolescents. A total of 42 out of 70 experts in child and adolescent psychiatry completed and returned the survey questionnaires. Results Antidepressant (AD) monotherapy was identified as the first-line treatment option for MDD of mild-to-moderate severity. For severe MDD without psychotic features in children and adolescents, both AD monotherapy and AD augmentation with atypical antipsychotics (AAPs) were recommended as first-line treatments. In cases of MDD with psychotic features, AD augmentation with AAPs was the preferred first-line treatment strategy. Conclusion We have developed a treatment algorithm specifically for child and adolescent populations with depressive disorders, offering enhanced specificity compared to the KMAP-DD 2021. It is anticipated that this algorithm will furnish clinicians with valuable information and facilitate the management of depressive disorders in children and adolescents.

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키워드

Major depressive disorder Pharmacotherapy Algorithm Children Adolescents 주요우울장애 약물치료 알고리듬 소아 청소년