Alloxan 투여가토(投與家兎)의 대사(代謝)에 미치는 Reserpine 의 효과(效果)

• 영문명: The Effect of Reserpine on the Metabolism of the Alloxan treated Rabbit
• 발행기관: 대한약리학회
• 저자명: 신경철(Shin, Kyung-Chul)
• 간행물 정보: 『대한약리학잡지』제5권 제2호, 81~86쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1969.12.31

영문 초록

Alloxan is a diabetogenic agent which destroys the beta-cell of the Langerhan s islet of pancreas and it disturbs the secretion of insulin. It is known that alloxan interfers with the hepatic enzyme activity and some aspect of the other metabolism. The author attempted to investigate the influence of reserpine upon the serum transaminase activity, blood sugar and serum total cholesterol contents of rabbit treated alloxan. The results obtained were summarized as follows; 1. The serum GOT and GPT activity of alloxanized rabbit pretreated with reserpine showed marked decrease compared with alloxan control group. 2. The blood sugar level of alloxanized rabbit pretreated with reserpine showed lower than the alloxan control group. 3. The total cholesterol level of alloxanized rabbit pretreated with reserpine was lower than that of alloxan control group.