우리나라 백부자(Aconitum Koreanum R. Raymond)의 적출 개구리 심장 운동에 대한 작용 및 LD50

• 영문명: The Action of Extracts of Aconitum Koreanum R. Raymond on isolated Frog heart and LD₅₀
• 발행기관: 대한약리학회
• 저자명: 박정순(Park, Chung-Soon) 김윤근(Kim, Yoon-Keun)
• 간행물 정보: 『대한약리학잡지』제5권 제2호, 75~80쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1969.12.31

영문 초록

Aconitum Koreanum rhizoma has been applied in therapy from old in oriental medicine (Korean Hanbang), The action of the water and alcohol extracts of the rhizoma and root of Aconitum Koreanum R. Raymond, a common herb in Korea, on the isolated Frog heart and LD₅₀ were observed. The results of the studies were as follows: 1. The cardiac effect in the concentration of the extracts(10^-3) was increased and duratrin of action prolonged approximately 10 minutes, but in the extracts(3 X 10^-3)blocked. 2. The LD₅₀ of extracts were 722 mg/kg (water) and 151mg/kg (alcohol) intraperitoneally in mice.