머위(Petasites japonicus) 추출물의 항산화와 항암활성 효과

• 영문명: The Antioxidant and Anticancer Effects of Butterbur (Petasites japonicus) Extracts
• 발행기관: 한국자원식물학회
• 저자명: 서훈석(Hun-Seok Seo) 정봉환(Bong-Hwan Chung) 조용구(Yong-Gu Cho)
• 간행물 정보: 『한국자원식물학회지』제21권 제4호, 265~269쪽, 전체 5쪽
• 주제분류: 농수해양 > 기타농수해양
• 파일형태: PDF
• 발행일자: 2008.08.31

영문 초록

The antioxidant activities of the extracts of butterbur (Petasites japonicus) derived from different extraction methods were investigated. SOD (superoxide dismutase)-like activity differed according to the extraction solvents, showing a greater antioxidant effect with ethanol solvent than that of water. Ethanol extracts of butterbur leaves showed higher SOD-like activity of 96.7% than those of water extracts. The contents of polyphenolic compounds were higher in water extracts than those in ethanol extracts. The highest content of polyphenolic compounds was 223mg/g dry weight for butterbur leaves. EDA of butterbur roots was 61.5% in the water extract and EDA in butterbur leaves was 34.9% in the ethanol extract. The anticancer effects with the extracts of butterbur were experimented by fractionations with different solvents. 41.9% of the growth of stomach cancer cells, SNU-719, were inhibited and also 72.7% of the growth of liver cancer cells, Hep3B, were inhibited by the butanol fractions of butterbur, while not affecting the growth of normal cell, DC 2.4.

목차

서언

재료 및 방법

결과 및 고찰

적요

인용문헌

키워드

SOD-like activity EDA (electron donating ability) Polyphenol Anticancer Stomach cancer Liver cancer