성인 코눈물관 부분폐쇄에서 실리콘관 삽입술 후 마이토마이신 점안의 효과

• 영문명: The Effect of Mitomycin C Instillation after Silicone Intubation in Adult Partial Nasolacrimal Duct Obstruction
• 발행기관: 대한안과학회
• 저자명: 정진구 안민,Jin Gu Jeong, MD, Min Ahn, MD,
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume53,number9, 1231~1235쪽, 전체 5쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2012.09.15

영문 초록

Purpose: To compare the result of mitomycin C (MMC) instillation after silicone intubation in partial nasolacrimal duct obstruction in adults according to duration of instillation. Methods: An instillation of 0.04% MMC eyedrops was performed on 61 eyes of 38 patients diagnosed with partial nasolacrimal duct obstruction. The clinical result of patient groups, classified according to duration of MMC eyedrops instillation, was analyzed prospectively. The patients groups was as follows: no MMC eyedrop instillation (group A), 1 week of MMC instillation (group B), 2 weeks of MMC instillation (group C), and 3 weeks of MMC instillation (group D). Results: Among all patients, 50 eyes (81.9%) showed improved symptoms. Fifteen eyes (71.4%) in group A, 8 eyes (72.7%) in group B, 13 eyes (86.7%) in group C and 14 eyes (100.0%) in group D had a successful outcome. The success rate was observed in groups D, C, B, and A, in descending order, which was statistically significant (p = 0.025). Conclusions: Silicone intubation is an effective treatment option for partial nasolacrimal duct obstruction in adults and MMC eyedrop instillation may improve silicone intubation results. J Korean Ophthalmol Soc 2012;53(9):1231-1235

키워드

Mitomycin-C, Nasolacrimal duct obstruction, Silicone intubation