실패한 섬유주절제술에 대한 마이토마이신 C를 사용한 섬유주절제술 재수술의 효과

• 영문명: Outcomes of Repeat Trabeculectomy with Mitomycin C for Previous Failed Trabeculectomy
• 발행기관: 대한안과학회
• 저자명: 윤영선 차순철,Young Sun Yun, M.D., Soon Cheol Cha, M.D.
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume46,number2, 297~305쪽, 전체 9쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2005.02.28

영문 초록

Purpose: To evaluate the safety and efficacy of repeat trabeculectomy with mitomycin C (MMC) in the management of previous failed trabeculectomy patients. Methods: We retrospectively reviewed the medical records of 44 eyes of 41 glaucoma patients who had been followed up for at least 6 months after repeat trabeculectomy with MMC and analyzed the success rates according to clinical factors, cumulative success rates, risk factors for surgical failure and complications. Surgical success was defined as an intraocular pressure (IOP) of 21 mmHg or less regardless of glaucoma medications and loss of vision. Results: Postoperative success was obtained in 34 (77.3%) out of 44 eyes after a mean follow-up period of 38.7 months. From Kaplan-Meier survival analysis, cumulative success rates after 6, 12, 24, and 36 months were 97.7%, 89.6%, 83.5%, and 80.1%, respectively. Success rates were significantly lower in eyes with preoperative IOP of 30 mmHg or more. Postoperative complications included transient hypotony in 7 eyes, choroidal detachment in 4, hyphema in 4, and cataract progression in 4. Conclusions: The success rates of repeat trabeculectomy may be lower than of primary trabeculectomy. However, considering the relatively high success rates and low complications of repeat trabeculectomy with MMC compared to the reported results of glaucoma drainage device implantation, repeat trabeculectomy with MMC is an effective and relatively safe surgical option as the secondary surgical procedure for previously failed trabeculectomy patients.

키워드

Failed trabeculectomy, Mitomycin C, Repeat trabeculectomy