다양한 신체증상을 주소로 내원한 부종양성 근강직증후군 1예

• 영문명: A Case of Paraneoplastic Stiff-Person Syndrome Presenting Multiple Somatic Symptoms
• 발행기관: 대한신경정신의학회
• 저자명: 명우재 강은호 유범희
• 간행물 정보: 『신경정신의학』제48권 제5호, 394~397쪽, 전체 4쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2009.09.30

영문 초록

Stiff-person syndrome (SPS) is an unusual autoimmune neurological disease. We report a woman who developed stiff-person syndrome associated with thymoma. A 42-year-old woman visited a general hospital complaining of progressive rigidity in her neck and both lower legs. She also had other symptoms including whole body pruritus, dysphargia, dysarthria, diplopia, and a visual hallucination- like symptom. Emotional distress preceded her symptoms. After a extensive neurologic workup, she was transferred from the neurologic ward to the psychiatric ward under the impression of conversion or somatoform disorder. During her psychiatric admission, we found a prolonged involuntary MUAP discharge on her electromyograph, and positive anti-GAD and anti-GQ1b antibodies. In addition, a chest CT scan revealed a thymic epithelial tumor. We report a case of stiff-person syndrome presenting multiple unexplained somatic symptoms, which was initially diagnosed as a conversion or somatoform disorder

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키워드

Stiff-person syndrome Thymoma Conversion disorder Somatoform disorder