장수와 치매의 예방

• 영문명: Longevity and Dementia Prevention
• 발행기관: 대한신경정신의학회
• 저자명: 전진숙
• 간행물 정보: 『신경정신의학』제48권 제5호, 307~313쪽, 전체 7쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2009.09.30

영문 초록

Objectives The aim of this study was to understand pharmacological and non-pharmacological methods of dementia prevention. Methods An internet searchof literature published from 2006 thru 2008 was done using combinations of the words‘dementia’ and‘prevention’. These publications were subsequently reviewed. Results 1) Reduction of risk factors：control of vascular risk factors (hypertension, diabetes mellitus, obesity, hypercholesterolemia, smoking, hyperhomocysteinemia, and platelet aggregation) and medical risk factors (head trauma, depression, herpes simplex, hyperthyroidism, and alcohol problems). 2) Pharmacological trial：NSAIDs, selective COX-2 inhibitors, estrogen replacement therapy, and antioxidants. 3) Healthy diet and nutrition：macronutrients (polyunsaturated fatty acid such as omega-3, alpha-linolenic acid, docosahexaenoic acid) and micronutrients (vitamins such as vitamin A, vitamin B1, 3, 6, 9, 12, vitamin C, vitamin D, vitamin E, vitamin K；minerals such as iron, iodine, magnesium, zinc, manganese, copper, cobalt, selenium；trace elements；and non-essential micronutrients such as polyphenols). 4) Regular excercise and activities：physical activities including aerobics, flexibility, and strength exerrcises；Recreational activities including participation in religious or social activities, healthy sex life with partner, and stimulating cognitive activities. ConclusionZZThe final goal of dementia treatment is primary prevention. However, there is no proven method to achieve this. Therefore, secondary prevention or preventative maintenance through risk reduction and introduction of a healthy lifestyle in an attempt to postpone the onset of disease is a realistic goal.

목차

서 론

치매의 과정과 위험인자

위험인자 감소

약물학적 예방

영양과 식사조절

신체적 운동과 기타 활동

결 론

REFERENCES

키워드

Dementia Primary prevention Secondary prevention Preventative maintenance Risk factor Lifestyle