Cohort profile: the Ewha Birth and Growth Study

• 발행기관: 한국역학회
• 저자명: Hye Ah Lee Bohyun Park Jungwon Min Eun Jeong Choi Ui Jeong Kim Hyun Jin Park Eun Ae Park Su Jin Cho Hae Soon Kim Hwayoung Lee Young Ju Kim Young Sun Hong Eui-Jung Kim Eun Hee Ha Hyesook Park
• 간행물 정보: 『Epidemiology and Health』43, 1~8쪽, 전체 8쪽
• 주제분류: 의약학 > 면역학
• 파일형태: PDF
• 발행일자: 2021.01.01

영문 초록

With the introduction of life-course epidemiology, researchers realized the importance of identifying risk factors in early life to prevent chronic diseases. This led to the establishment of the Ewha Birth and Growth Study in 2001; the study is a prospective birth cohort designed to provide evidence of early life risk factors for a child’s growth and health. Participants were recruited from those who visited Ewha Womans University Mokdong Hospital (a tertiary hospital in southwest Seoul, Korea) for prenatal care at 24-28 weeks of gestation. In total, 891 mothers enrolled in this study between 2001 and 2006 and their offspring (n=940) were followed-up. Regular check-up examinations of offspring were conducted at 3 years, 5 years, and 7 years of age and every year thereafter. To consider age-related health issues, extensive data were collected using questionnaires and measurements. In 2021, the study subjects will reach 19 years of age, and we are planning a check-up examination for early adulthood. About 20 years have passed since the cohort data were collected, and we have published results on childhood health outcomes associated with prenatal and birth characteristics, genetic and epigenetic characteristics related to childhood metabolism, the effects of exposure to endocrine disruptors, and dietary patterns in childhood. Recently, we started reporting on topics related to adolescent health. The findings will facilitate identification of early life risk factors for chronic diseases and the development of interventions for diseases later in life.

목차

INTRODUCTION

STUDY PARTICIPANTS

MEASUREMENTS

KEY FINDINGS

STRENGTHS AND WEAKNESSES

DATA ACCESSIBILITY

SUPPLEMENTARY MATERIALS

CONFLICT OF INTEREST

FUNDING

ACKNOWLEDGEMENTS

AUTHOR CONTRIBUTIONS

ORCID

REFERENCES

키워드

Cohort studies Child health Cardiometabolic risk factors Metabolic syndrome