빛간섭단층촬영을 이용한 상측분절시신경형성부전 환자의 망막신경섬유층 두께 분석

• 영문명: Analysis of Retinal Nerve Fiber Layer Thickness in Patients With Superior Segmental Optic Hypoplasia
• 발행기관: 대한안과학회
• 저자명: 서정원 박인원 정윤석,Jeong Won Seo, MD, In Won Park, MD, Yun Suk Chung, MD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume50,number1, 139~144쪽, 전체 6쪽
• 주제분류: 인문학 > 역사학
• 파일형태: PDF
• 발행일자: 2009.01.15

영문 초록

Purpose: To analyze the thickness of the peripapillary retinal nerve fiber layer (RNFL) in patients with superior segmental optic hypoplasia (SSOH) using optical coherence tomography (OCT). Methods: Ten eyes of 10 patients with SSOH and 20 eyes of 20 subjects as normal control were evaluated. The peripapillary RNFL thickness measured by Stratus OCT was compared between the two groups. Results: The mean RNFL thickness was significantly different between SSOH patients (72.35±14.77 μm) and normal subjects (111.61±6.62 μm) (p<0.001). The extent to which the RNFL thickness was below 5 percentile of normal subjects on the TSNIT graph was from the 41.7±15.53 to 110.1±7.47 scan number, which corresponded mainly with the superior nasal region. Moreover, in a clock‐hour analysis, the peripapillary RNFL thickness of the SSOH patients decreased significantly from 10 o\'clock to 6 o\'clock compared to normal subjects (p<0.01). Conclusions: Peripapillary RNFL thickness in patients with SSOH was reduced in the superior, nasal, and inferior regions. Further studies involving larger populations of patients should be performed to verify these findings.

키워드

Optical coherence tomography (OCT), RNFL thickness, Superior segmental optic hypoplasia (SSOH), Topless optic disc syndrome