Thalictrum uchiyamai Nakai의 항균작용에 관한 연구

• 영문명: Study on the Antimicrobial Activity of Thalictrum uchiyamai Nakai
• 발행기관: 대한약학회
• 저자명: 이인란(Ihn Rhan Lee) 이지영(Gee Young Lee)
• 간행물 정보: 『약학회지』제25권 제4호 (1981년), 199~204쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1981.12.30

영문 초록

The methanol extract of Thalictrum uchiyamai Nakai was fractionated into four parts; (1) ether soluble nonphenolic fraction (2) phenolic tertiary bases fraction, (3) chloroform soluble tertiary bases fraction and (4) aqueous quaternary bases fraction. The fractions of this plant showed a total of twenty-four spots on the silica gel TLC. Ether soluble nonphenolic fraction and ether soluble phenolic fraction showed nine alkaloid spots respectively, chloroform soluble fraction showed three alkaloid spots and quaternary bases fraction showed three alkaloid spots. The antimicrobial activity of the four extracts was shown as follows: nonphenolic tertiary bases inhibited the growth of Micrococcus dutica at the concentration of 50mcg/ml, in phenolic tertiary bases 500mcg/ml concentration was inhibitory to Micrococcus dutica and to Staphylococcus aureus. In aqueous quaternary bases, 500mcg/ml concentration was inhibitory to Klebsiella pneumoniae. Chloroform soluble tertiary fraction showed slight activity. All of bases showed reproducible activity againt tested microorganisms.