저농도 유기용제 노출 사업장 근로자의 심혈관질환 위험인자 변화 추적(2008~2012)

• 영문명: Five Year’s Follow-up of the Cardiovascular Disease Risk Factors among the Low Level Organic Solvent Exposure Workers
• 발행기관: 한국직업건강간호학회
• 저자명: 김미애(Kim, Mi-Ae)
• 간행물 정보: 『한국직업건강간호학회지』제24권 제2호, 67~75쪽, 전체 9쪽
• 주제분류: 의약학 > 간호학
• 파일형태: PDF
• 발행일자: 2015.05.31

영문 초록

Purpose: The objective of the present study was to evaluate the effects of occupational exposure to low dose organic solvents on the prevalence of cardiovascular risk factors. Methods: Study design was retrospective cohort study subjected on 191 exposures and 118 controls working in a petrochemical manufacture company. The eight indicators related to CVD risk were followed up for five years from 2008 to 2012. The risk level was compared during the follow up years and subject’s characteristics, and the change of risk level were analyzed with repeated measures ANOVA and multiple logistic regression analysis. Results: At the start year 2008, the rate over cutoff value (ROCV) of BS (p<.001) and mean systolic BP (p=.017) were higher in organic solvent exposure group and the others showed no difference. And by the subject’s characteristics, odds ratio of the ROCV of BS were higher in organic solvent exposure group and work shift group as 2.51 and 3.07. Comparing the results in 2012 to those of 2008, cardiovascular disease risk in organic solvent exposure group was about 1.5 times higher than that of in the control group. Conclusion: Gradual increase in the CVD risk was identified in organic solvent exposure group. However, the risk might be influenced by shift work and bad behaviors rather than organic solvent exposure.

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키워드

심혈관질환 유기용제 저농도 5년 추적관찰 Cardiovascular disease Organic solvent Low dose 5 years follow-up