강박장애 환자의 인지기능이상에 대한 2년 추적 연구

• 영문명: Cognitive Dysfunctions in Patients with Obsessive-Compulsive Disorder： Two-Year Treatment Follow-up
• 발행기관: 대한신경정신의학회
• 저자명: 노규식 신민섭 박희수 하태현 신용욱 김명선 권준수
• 간행물 정보: 『신경정신의학』제43권 제5호, 577~582쪽, 전체 6쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2004.09.30

영문 초록

Objectives：The purpose of this study was to investigate the changes of cognitive dysfunctions in patients with obsessivecompulsive disorder (OCD) over the two-year of pharmacological treatment. Methods：The thirty-three OCD patients and thirteen normal subjects were administered the neuropsychological tests and clinical evaluations twice (at the baseline and two-year). Results：In spite of the two-year treatment, the accuracy of delayed recall on the Rey-Osterrieth Complex Figure Tests (RCFT), the numbers of responses on the category and letter test of Controlled Oral Word Association Test (COWA), the response time on the Trail Making Test part A (TMT-A) remained significantly impaired in the OCD patients compared with the normal controls. Conclusion：These findings suggest that the cognitive dysfunctions such as visuospatial memory and verbal fluency might be the underlying persisting neuropathophysiology of OCD.

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키워드

Obsessive-compulsive disorder Rey-osterrieth complex figure tests Controlled oral word association test Cognitive dysfunctions