정신분열병 및 우울장애 환자에서 무쾌감증의 특성 비교

• 영문명: Comparison of the Characteristics of Anhedonia between Patients with Schizophrenia and Depressive Disorder
• 발행기관: 대한신경정신의학회
• 저자명: 최수희 박일호 구정훈 최경묵 박민경 김재진
• 간행물 정보: 『신경정신의학』제49권 제6호, 570~577쪽, 전체 8쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2010.11.30

영문 초록

Objectives Anhedonia, defined as an inability to experience pleasure, has been considered to be a core feature of schizophrenia and depression. The purpose of the present study was to compare the specific characteristics of anhedonia in patients with the two illnesses by examining hedonic capacity during phased hedonic experience. Methods Hedonic rating tasks, using the film clips of physical and social hedonic stimuli and neutral stimuli, were performed by 29 patients with schizophrenia, 20 patients with depression, and 29 normal controls. Each task consisted of ‘preview phase’ with insufficient emotional information, and a subsequent ‘theme phase’ with sufficient emotional information. Results In normal controls, the mean hedonic score was increased in the theme phase compared with the preview phase, suggesting an appropriate augmentation of the hedonic response. In patients with schizophrenia, hedonic scores in the preview phase were comparable with those in normal controls, but showed deficient augmentation in the theme phase. In patients with depressive disorder, the range of increments in scores between the preview and theme phases was normal, but the scores themselves were lower in both phases than in the other two groups. Conclusion The results indicate that patients with schizophrenia show a deficient augmentation of the hedonic response, whereas patients with depressive disorder have a pervasive lack of hedonic capacity.

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키워드

Anhedonia Hedonic capacity Schizophrenia Depressive disorder