만성정신분열증 환자에서 Cholecystokinin의 치료효과

• 영문명: The Effect of Cholecystokinin in the Treatment of Chronic Schizophrenic Patients
• 발행기관: 대한신경정신의학회
• 저자명: 이창욱 김보연 최중철 백인호
• 간행물 정보: 『신경정신의학』제33권 제2호, 439~443쪽, 전체 5쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 1994.03.30

영문 초록

This study was designed to investigate antipsychotic properties of cholecystokinin-octapeptide (CCK-8) in schizophrenic patients. Subjects were 30 chronic schizophrenics with residual symptoms following stablization with antipsychotic drugs. CCK-8 (0.2jig/kg) or placebo was administered intravenously single injection with double-blind method while patients received constant dose of antipsychotic drugs. The clinical effect of CCK-8 was evaluated with BPRS which was applied to patients 2 hours before and 3 and 7 days after drug administration. Results showed no significant differences between CCK-8 group and placebo group.

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키워드

CCK-8 Chronic schizophrenia