한약 기반 복합물의 피부 항노화 및 항염증 효과 분석

• 영문명: Analysis of the Anti-aging and Anti-inflammatory Effects of Herbal Medicine-Based Complex
• 발행기관: 한국응용과학기술학회 (구.한국유화학회)
• 저자명: 주철희(Cheol-Hee Ju) 정영환(Yeong Hwan Jeong) 김동연(Dong-Yeon Kim) 박수진(Su-jin Park) 김현정(Hyun-jeong Kim) 장영아(Young-Ah Jang)
• 간행물 정보: 『한국응용과학기술학회지』제41권 제6호, 1637~1647쪽, 전체 11쪽
• 주제분류: 공학 > 화학공학
• 파일형태: PDF
• 발행일자: 2024.12.31

국문 초록

The cosmetics industry expects skin improvement and anti-aging effects by using natural products and natural extracts. In particular, herbal extracts are ingredients with traditionally proven pharmacological efficacy, and are in the spotlight as effective ingredients for maintaining skin health and improving skin troubles. In this study, the antioxidant, anti-inflammation, and wrinkle improvement effects were evaluated by using herbal ingredients such as Dioscorea opposita, Angelica dahurica, Rehmannia glutinosa, Panax ginseng and Ophiopogon japonicus. The antioxidant activity of the herbal complex was confirmed by measuring DPPH and ABTS+ radical scavenging activity, and after a cytotoxicity test using the MTT assay, it showed a concentration-dependent inhibition effect on NO production by LPS stimulation in RAW 264.7 cells. In addition, in the analysis of MMP-1, MMP-2 and procollagen gene expression induced by H2O2 in HDF cells, the expression of MMP-1 was suppressed in a dose-dependent manner by the herbal complexes. This is expected to make a significant contribution to wrinkle improvement and skin elasticity enhancement. These results suggest that herbal complexes can be used as promising cosmetic materials for skin improvement and anti-aging.

목차

1. 서 론

2. 실 험

3. 결과 및 고찰

4. 결 론

감사의 글

References

키워드

Herbal Complex Antioxidant Anti-inflammatory Matrix Metalloproteinases Skin Aging