Performance of and Pressure Elevation Formed by Small-diameter Microtubes Used in Constant-flow Sets

• 발행기관: 대한안과학회
• 저자명: Sae Woon Sohn Myounggyu D. Noh Jong-Hyun Lee Kyoung Nam Kim Chang-sik Kim Byung Heon Ahn
• 간행물 정보: 『The Korean Journal of Ophthalmology』Vol.30 No.3, 225~233쪽, 전체 9쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2016.06.30

영문 초록

Purpose: We explored the performance of and pressure elevation caused by small-diameter microtubes used to reduce overfiltration. Methods: Using a syringe pump-driven constant-flow setting (2 μL/min), pressures were measured for polytetrafluoroethylene(PTFE) microtubes 5 mm in length with inner diameters of 51, 64, and 76 μm and for polyether block amide (PEBAX) microtubes with an inner diameter of 76 μm. Experiments (using microtubes only) were initially performed in air, water, and enucleated pig eyes and were repeated under the same conditions using intraluminal 9/0 nylon stents. Results: The pressures measured in air in 51-, 64-, and 76-μm-diameter PTFE microtubes differed significantly (22.1, 16.9, and 12.2 mmHg, respectively; p < 0.001), and that of the 76-μm-diameter PEBAX microtube was 15.8 mmHg (p < 0.001 compared to the 12.2 mmHg of the 76-μm-diameter PTFE microtube). The pressures measured in water also differed significantly among the three microtubes at 3.9, 3.0, and 1.4 mmHg, respectively, while that in the PEBAX microtube was 2.6 mmHg (all p < 0.001). Using the intraluminal stent, the pressure in water of the three different PTFE microtubes increased to 22.6, 18.0, and 4.1 mmHg, respectively, and that in the PEBAX microtube increased to 10.5 mmHg (all p < 0.001). Similar trends were evident when measurements were performed in pig eyes. Conclusions: Although microtubes of smaller diameter experienced higher pressure in air, reduction of the inner diameter to 51 μm did not adequately increase the pressure attained in water or pig eyes. Insertion of an intraluminal stent effectively elevated the latter pressures. PEBAX microtubes created higher pressures than did PTFE microtubes.

목차

Materials and Methods

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Discussion

Conflict of Interest

Acknowledgements

References

키워드

Intraluminal stent Intraocular pressure Microtube Polyether block amide Polytetrafluoroethylene