가토 대퇴골골에 중첩이식된 단순냉동 및 냉동 건조 동종골의 치유과정에 관한 실험적 연구

• 영문명: The repari of the onlay frozen and freeze-dried allogeneic bone in rabbit
• 발행기관: 대한구강악안면외과학회
• 저자명: 정호용(Ho Yong Chung) 이동근(Dong Keun Lee) 엄인웅(In Woong Um) 신기영(Ki Young Shin) 우승철(Seung Chul Woo)
• 간행물 정보: 『대한구강악안면외과학회지』대한구강악안면외과학회지 제20권 제2호, 149~161쪽, 전체 13쪽
• 주제분류: 의약학 > 내과학
• 파일형태: PDF
• 발행일자: 1994.04.30

영문 초록

The use of autologous bone grafts for ridge augmentation is widely accepted. However, the development of other bone graft substitutes reduced the importance of the site from which grafting material is taken. Allogeneic bone grafts are a potential alternative. The variables that may influence the results of allogeneic bone grafts, are whether the grafts are cortical or cancellous, chips or blocks, undecalcified or fully decalcified, deep freeting or freeze-dried, etc.. In an experimental study of the femurs of rabbits on which the onlay undecalcified cortical bone grafts were performed, we observed the histologic differences between deep forzen and freeze-dried cortical allogeneic bone grafts on the healing and repair processes. These results can be compared to those from autologous bone grafts. The from autologous bone were: 1. The inflammatory reaction with macrophages and lymphocytes were observed in the first week, but disappeared before 4 weeks. The inflammatory reaction was more severe in the deep frozen group. 2. In the freeze-dried group, the bony union was earlier than the deep frozen group. 3. The osteoblastic activity of grafts increased for the first 6 weeks then decreased slightly by 8 weeks. Osteoblasts were more active in the autologous and freeze-dried groups. 4. New bone formation was slower in the deep frozen group in the first two weeks, but after two weeks there were no distinguishable differences between the groups. 5. The bone resorptions around the grafts continued far 6 weeks after the operation. The bone resorptions were greater in the deep frozen group. 6. More capillary proliferations in the intersurfaces and grafts were observed in the autologous and freeze-dried group. In the results as written above, the freeze-dried group was superior to deep frozen group in the healing process, but in fact, there were considered that the undecalcified, freeze-dried or deep frozen allogeneic bones could be used in the onlay graft for augmentation of jaws.

목차

Abstract

I. 서론

II. 연구 재료 및 방법

III. 연구성적

IV. 총괄 및 고찰

V. 결론

참고문헌

키워드

onlay graft allogeneic bone freeze-dried deep frozen