난치성 봄철각결막염에서 유두절제술과 상안검판 트리암시놀론 주사의 동시 치료 효과

• 영문명: Effect of Treatment With Excision of Papillae and Supratarsal Triamcinolone Injection on Refractory Vernal Keratoconjunctivitis
• 발행기관: 대한안과학회
• 저자명: 최원 임성규 윤경철,Won Choi, MD, Seong-Gyu Lim, MD, Kyung Chul Yoon, MD, PhD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume51,number4, 492~497쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2010.04.15

영문 초록

Purpose: To evaluate the therapeutic effect of the combined treatment of excision of the papillae and a supratarsal injection of triamcinolone on refractory vernal keratoconjunctivitis (VKC). Methods: Twenty-three eyes of 14 patients with refractory vernal keratoconjunctivitis were included. Patients were treated with the combined excision of papillae and supratarsal injection of triamcinolone. Best corrected visual acuity (BCVA), intraocular pressure, symptoms of itching, tearing, discomfort, secretion and epiphora, and signs including limbal hypertrophy, hyperemia, papilla size, keratitis, corneal neovascularization and blepharitis were evaluated before and two weeks, four weeks, and eight weeks after treatment. The CCL11 level in the tears of each eye were analyzed before and two weeks after treatment. Results: The mean scores of subjective symptoms and objective signs as well as BCVA were significantly improved two weeks after treatment. CCL11 levels in the tears were 389.5±474.9 pg/ml before treatment and were undetectable two weeks after treatment. Improvement of symptom and sign parameters was maintained up to eight weeks after treatment. However, seven eyes (30.4%) recurred within two weeks after treatment. Conclusions: Combined excision of the papillae and a supratarsal injection of triamcinolone may be effective in the treatment of refractory VKC. J Korean Ophthalmol Soc 2010;51(4):492-497

키워드

Combined treatment, Papillectomy, Triamcinolone, VKC