화학요법제 합성연구 III Thiosemicarbazone 유도체의 합성 및 항균성

• 영문명: Synthetic Studies on Chemotherapeutic Agents. III. Synthesis and Antimicrobial Activity of Some Thiosemicarbazone Derivatives
• 발행기관: 대한약학회
• 저자명: 조윤성(Yun Sung Chough) 김원호(Won Ho Kim)
• 간행물 정보: 『약학회지』제15권 제3&4호 (1971년), 93~97쪽, 전체 5쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1971.12.31

영문 초록

Seventeen novel compounds of thiosemicarbazone derivatives were synthesized and evaluated for their in vitro antitubercular activity against Mycobacterium tuberculosis H37Rv and antibacterial activity against Staphylococcus aureus, Escherichia coli. It was found that 4-(alpha-naphthyl)-1-(2-furfuraldehyde)-3-thiosemicarbazone was active at 0.01mcg/ml against E.Coli, respectively.