조혈제 제조에 관한 연구 III 지효성제형화에 대하여

• 영문명: Study on the Preparation of Ferruginous Hematinics. III. A Study on the Preparation of Sustained-Release Formed Ferruginous Hematinics
• 발행기관: 대한약학회
• 저자명: 나운룡(Woon Lyong Lah)
• 간행물 정보: 『약학회지』제15권 제3&4호 (1971년), 79~82쪽, 전체 4쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1971.12.31

영문 초록

In order to compare the iron concentrations of the marketed ferruginous hematinics with the sustained-release dosage forms and to prepare the good hematinic which can be absorbed effectively without forming "iron block" in the gastrointestinal tract, gelatinized micropellets containing medicament were prepared and hardened in 10% formalin-isopropanol in the time of 72 hours. These micropellets were digested with artificial gastric juice and plotted a curve of released iron concentration. As a result, it is found that gelatinized micropellets sustained-release dosage form is an excellent ferruginous hematinic and it is shown that several marketed preparations can be improved in their hematinic actions by forming the sustained-release dosage.