수종 탄닌의 역전사효소와 HIV-1 복제 저해활성

• 영문명: Inhibitory Activities of Tannins against Reverse Transcriptase and HIV-1 Replication
• 발행기관: 대한약학회
• 저자명: 김영호(Young Ho Kim) 이성우(Sung Woo Lee) 김항섭(Hang Sub Kim) 이승호(Seung Ho Lee) 송만기(Man Ki Song) 성영철(Young Chul Sung) 이정준(Jung Joon Lee)
• 간행물 정보: 『약학회지』제39권 제5호 (1995년), 560~564쪽, 전체 5쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1995.10.30

영문 초록

Thirty ellagitannins originated from some Euphorbiaceous plants were tested for the inhibitory activities against AMV reverse transcriptase and replication of HIV-1 using syncytia forming assay. Most of ellagitannins showed strong inhibitory activities against AMV reverse transcriptase. Some ellagitannins including geraniin, mallotusinin, elaeocarpusin, euphorscopin and jolkianin, showed significant inhibitory activities of syncytia formation of supT1 cell line.