Overproduction of anthocyanin in ginseng hairy roots enhances their antioxidant, antimicrobial, and anti-elastase activities

• 발행기관: (사)한국식물생명공학회
• 저자명: 진소라(Sora Jin) 방성훈(Seounggun Bang) 안민아(Min-A Ahn) 이규빈(Kyubin Lee) 김경환(Kyunghwan Kim) 현태경(Tae Kyung Hy
• 간행물 정보: 『Journal of Plant Biotechnology』48권 2호, 100~105쪽, 전체 6쪽
• 주제분류: 농수해양 > 기타농수해양
• 파일형태: PDF
• 발행일자: 2021.06.30

영문 초록

Genetic engineering is a potential approach to improve secondary metabolism in plants. In order to elucidate the effect of production of anthocyanin pigment 1 (PAP1) overexpression on the bioactivity of ginseng, we analyzed its antioxidant, antimicrobial, and anti-elastase activities in this study. Our results showed that PAP1 overexpression increased the production of polyphenolic compounds including anthocyanins. The antioxidant, antimicrobial, and anti-elastase activities were stronger in anthocyanin-overproducing ginseng hairy roots (AOX) than in wild ginseng hairy roots. Using a different solvent system (0, 30, 70, and 100% (v/v) EtOH), we revealed that variations in the contents of the polyphenolic compounds were highly correlated with changes in the antioxidant and antimicrobial activities of AOX. The antioxidant, antimicrobial, and anti-elastase effects of AOX highlight genetic engineering as a powerful approach to enhance the therapeutic properties of plants. Our results show that AOX could potentially have various functional applications in the cosmetic and pharmaceutical industries

목차

Introduction

Materials and methods

Results and discussion

Conclusion

Acknowledgements

References

키워드

Antioxidant activity Anthocyanin Antimicrobial activity Ginseng hairy root