학술논문
Autophagy in neutrophils
이용수 14
- 영문명
- 발행기관
- 대한생리학회-대한약리학회
- 저자명
- Sanjeeb Shrestha Jae Man Lee Chang-Won Hong
- 간행물 정보
- 『The Korean Journal of Physiology & Pharmacology』제24권 제1호, 1~10쪽, 전체 10쪽
- 주제분류
- 의약학 > 의학일반
- 파일형태
- 발행일자
- 2020.01.31
4,000원
구매일시로부터 72시간 이내에 다운로드 가능합니다.
이 학술논문 정보는 (주)교보문고와 각 발행기관 사이에 저작물 이용 계약이 체결된 것으로, 교보문고를 통해 제공되고 있습니다.
국문 초록
영문 초록
Autophagy is a highly conserved intracellular degradation and energyrecycling mechanism that contributes to the maintenance of cellular homeostasis.
Extensive researches over the past decades have defined the role of autophagy innate immune cells. In this review, we describe the current state of knowledge regarding the role of autophagy in neutrophil biology and a picture of molecular mechanism underlying autophagy in neutrophils. Neutrophils are professional phagocytes that comprise the first line of defense against pathogen. Autophagy machineries are highly conserved in neutrophils. Autophagy is not only involved in generalized function of neutrophils such as differentiation in bone marrow but also plays crucial role effector functions of neutrophils such as granule formation, degranulation, neutrophil extracellular traps release, cytokine production, bactericidal activity and controlling inflammation. This review outlines the current understanding of autophagy in neutrophils and provides insight towards identification of novel therapeutics targeting autophagy in neutrophils.
목차
INTRODUCTION
OVERVIEW OF AUTOPHAGY PATHWAYS
AUTOPHAGY IN NEUTROPHIL DIFFERENTIATION
AUTOPHAGY IN NEUTROPHIL BACTERICIDAL ACTIVITY
AUTOPHAGY AND NETosis
AUTOPHAGY AND NEUTROPHIL GRANULE FORMATION/DEGRANULATION
AUTOPHAGY AND NEUTROPHIL-MEDIATED INFLAMMATION/PATHOLOGY
CONCLUSIONS
해당간행물 수록 논문
- Analysis of interaction between intracellular spermine and transient receptor potential canonical 4 channel: multiple candidate sites of negatively charged amino acids for the inward rectification of transient receptor potential canonical 4
- Interaction of genetic background and exercise training intensity on endothelial function in mouse aorta
- Autophagy in neutrophils
- Quercetin-induced apoptosis ameliorates vascular smooth muscle cell senescence through AMP-activated protein kinase signaling pathway
- Ezrin-radixin-moesin proteins are regulated by Akt-GSK3β signaling in the rat nucleus accumbens core
- Neuroprotective potential of imatinib in global ischemiareperfusion- induced cerebral injury: possible role of Janus-activated kinase 2/signal transducer and activator of transcription 3 and connexin 43
- Spatiotemporal expression of RCAN1 and its isoform RCAN1-4 in the mouse hippocampus after pilocarpine-induced status epilepticus
- β-Sitosterol treatment attenuates cognitive deficits and prevents amyloid plaque deposition in amyloid protein precursor/ presenilin 1 mice
- Inhibitory effect of carvacrol on lipopolysaccharide-induced memory impairment in rats
- Medium- and long-chain triglyceride propofol reduces the activity of acetyl-coenzyme A carboxylase in hepatic lipid metabolism in HepG2 and Huh7 cells
- Decreased inward rectifier and voltage-gated K+ currents of the right septal coronary artery smooth muscle cells in pulmonary arterial hypertensive rats
- Bordetella bronchiseptica is a potent and safe adjuvant that enhances the antigen-presenting capability of dendritic cells
- Feasibility of fully automated classification of whole slide images based on deep learning
참고문헌
교보eBook 첫 방문을 환영 합니다!
신규가입 혜택 지급이 완료 되었습니다.
바로 사용 가능한 교보e캐시 1,000원 (유효기간 7일)
지금 바로 교보eBook의 다양한 콘텐츠를 이용해 보세요!