Breast lymphoscintigraphy 검사 시 체표윤곽을 나타내는 방법의 비교

• 영문명: The comparison of lesion localization methods in breast lymphoscintigraphy
• 발행기관: 대한핵의학기술학회
• 저자명: 연준호(Joon ho Yeon) 홍건철(Gun chul Hong) 김수영(Soo yung Kim) 최성욱(Sung wook Choi)
• 간행물 정보: 『핵의학기술』Vol.19 No.2, 74~80쪽, 전체 7쪽
• 주제분류: 의약학 > 방사선과학
• 파일형태: PDF
• 발행일자: 2015.10.30

영문 초록

Purpose Breast lymphoscintigraphy is an important technique to present for body surface precisely, which shows a lymph node metastasis of malignant tumors at an early stage and is performed before and after surgery in patients with breast cancer. In this study, we evaluated several methods of body outline imaging to present exact location of lesions, as well as compared respective exposure doses. Materials and Methods RANDO phantom and SYMBIA T-16 were used for obtaining imaging. A lesion and an injection site were created by inserting a point source of 0.11 M㏃ on the axillary sentinel lymph node and 37 M㏃ on the right breast, respectively. The first method for acquiring the image was used by drawing the body surface of phantom for 30 sec using Na ⁹⁹ᵐTcO₄ as a point source. The second, the image was acquired with ⁵⁷Co flood source for 30 seconds on the rear side and the left side of the phantom, the image as the third method was obtained using a syringe filled with 37 M㏃ of Na ⁹⁹ᵐTcO₄ in 10 ㎖ of saline, and as the fourth, we used a photon energy and scatter energy of ⁹⁹ᵐTc emitting from phantom without any addition radiation exposure. Finally, the image was fused the scout image and the basal image of SPECT/CT using MATLAB® program. Anterior and lateral images were acquired for 3 min, and radiation exposure was measured by the personal exposure dosimeter. We conducted preference of 10 images from nuclear medicine doctors by the survey. Results TBR values of anterior and right image in the first to fifth method were 334.9 and 117.2 (1st), 266.1 and 124.4 (2nd), 117.4 and 99.6 (3ʳᵈ), 3.2 and 7.6 (4ᵗʰ), and 565.6 and 141.8 (5ᵗʰ). And also exposure doses of these method were 2, 2, 2, 0, and 30 μ㏜, respectively. Among five methods, the fifth method showed the highest TBR value as well as exposure dose, where as the fourth method showed the lowest TBR value and exposure dose. As a result, the last method (5ᵗʰ)is the best method and the fourth method is the worst method in this study. Conclusion Scout method of SPECT/CT can be useful that provides the best values of TBR and the best score of survey result. Even though personal exposure dose when patients take scout of SPECT/CT was higher than another scan, it was slight level comparison to 1 m㏜ as the dose limit to non-radiation workers. If the scout is possible to less than 80 kV, exposure dose can be reduced, and also useful lesion localization provided.

목차

서론

실험 재료 및 방법

결과

결론

요약

참고문헌

키워드

Breast lymphoscintigraphy scout scan TBR(Tumor to Background Ratio) exposure dose