A rare histopathological variant of Schwannoma with rosette-like arrangements and epithelioid cells: a case report from a histopathologist’s perspective

• 영문명: A rare histopathological variant of Schwannoma with rosette-like arrangements and epithelioid cells: a case report from a histopathologist’s perspective
• 발행기관: 대한구강악안면외과학회
• 저자명: Monica Mehendiratta Vikas Kumar Sant Manisha Lakhanpal Keerti Chauhan
• 간행물 정보: 『대한구강악안면외과학회지』제49권 제4호, 233~238쪽, 전체 6쪽
• 주제분류: 의약학 > 내과학
• 파일형태: PDF
• 발행일자: 2023.08.31

영문 초록

Schwannomas exhibit histopathological variation that leads to diagnostic dilemmas, although less frequent in the oral cavity. We describe a case with unique histopathology and no relevant clinical history that adds to the breadth of literature on the diversity presented by Schwannoma. A 60-year-old female patient presented with a small dome-shaped, asymptomatic swelling on the alveolar ridge 6 years in duration. Histopathologically, it showed rich cellular pathology with a unique arrangement of tumor cells forming irregular rosettes. Each rosette presented with a central core of fibrincollagenous material and the tumor cells were arranged on the periphery, exhibiting epithelioid change with evidence of mild cellular and nuclear pleomorphism. On immunohistochemical evaluation, the cells were strongly and diffusely positive for S-100 and negative for Ki-67. A diagnosis of benign Schwannoma with a rosette-like arrangement with epithelioid change was made. The case report emphasizes the risk of misdiagnosis and the importance of awareness regarding rare histopathological variants of Schwannoma.

목차

I. Introduction

II. Case Report

III. Discussion

ORCID

Authors’ Contributions

Funding

Acknowledgements

Consent for Publishing Photographs

Conflict of Interest

References

키워드

Epithelioid cells Verocay bodies Neurilemmoma Collagen Rosette