Comparison of radical prostatectomy and external beam radiotherapy in high-risk prostate cancer

• 발행기관: 대한방사선종양학회
• 저자명: Seok-Joo Chun Jin Ho Kim Ja Hyeon Ku Cheol Kwak Eun Sik Lee Suzy Kim
• 간행물 정보: 『대한방사선종양학회지』제39권 제3호, 231~238쪽, 전체 8쪽
• 주제분류: 의약학 > 종양학
• 파일형태: PDF
• 발행일자: 2021.09.30

영문 초록

Purpose: We evaluated clinical outcomes of high-risk prostate cancer patients receiving external beam radiotherapy (EBRT) or radical prostatectomy (RP). Materials and Methods: Patients were classified as high-risk prostate cancer and received definitive treatment between 2005 and 2015. Patients with previous pelvic radiotherapy, positive lymph node or distant metastasis were excluded. The primary outcomes were prostate cancer-specific survival (PCSS) and distant metastasis-free survival (DMFS). Results: Of 583 patients met the inclusion criteria (77 EBRT and 506 RP), the estimated 10-year PCSS was 97.0% in the RP and 95.9% in the EBRT (p = 0.770). No significant difference was seen in the DMFS (p = 0.540), whereas there was a trend in favor of RP over EBRT in overall survival (OS) (p = 0.068). Propensity score matching analysis with confounding variables was done, with 183 patients (66 EBRT and 117 RP) were included. No significant difference in DMFS, PCSS or OS was found. Conclusion: Our data demonstrated similar oncologic PCSS, OS, and DMFS outcomes between EBRT and RP patients.

목차

Introduction

Materials and Methods

Results

Discussion and Conclusion

Conflict of Interest

References

키워드

Radiotherapy Prostatectomy Prostatic neoplasms