우측 이하선에서 재발한 기무라병 증례 보고

• 영문명: Kimura Disease Recurred in the Right Parotid Gland: A Case Report
• 발행기관: 대한두경부종양학회
• 저자명: 김주영(Juyoung Kim) 허영균(Young Kyun Hur) 김경환(Kyung Hwan Kim) 심남석(Nam Suk Sim)
• 간행물 정보: 『대한두경부종양학회지』제41권 제1호, 13~16쪽, 전체 4쪽
• 주제분류: 의약학 > 종양학
• 파일형태: PDF
• 발행일자: 2025.05.31

국문 초록

Kimura’s disease is a rare, chronic inflammatory disorder that typically presents as painless head and neck masses in young Asian males, often accompanied by peripheral eosinophilia and elevated IgE levels. We report a case of recurrent Kimura’s disease involving the right parotid gland in a 35-year-old man, previously treated surgically. Due to tumor size (6 cm) and high risk of surgical complications, the patient underwent radiotherapy (30 Gy/15 fractions). Post-treatment imaging showed significant tumor reduction with no adverse effects or recurrence during 12 months of follow-up. While surgery remains the mainstay of treatment, recent studies suggest that radiotherapy or immunosuppressive therapy may be effective, especially in cases at high risk of recurrence. A recent meta-analysis identified tumor size ≥3 cm, prolonged disease duration (5 years), high eosinophil percentage (20%), and elevated IgE (10,000 IU/ml) as significant recurrence predictors. This case supports that radiotherapy may sere as a valuable treatment option when surgery in contraindicated or in high-risk recurrent cases.

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키워드

Kimura’s disease Parotid Radiotherapy Recurrence