M 약침의 항산화 및 항염 활성에 대한 연구

• 영문명: Anti-oxidant and Anti-inflammatory Effects of M Yakchim
• 발행기관: 임상약침학회
• 저자명: 안덕근(Duck-Gun An) 황지혜(Ji-Hye Hwang) 정진호(Jin-Ho Jeong)
• 간행물 정보: 『임상약침학회학회지』대한면역약침학회지 제4권 제2호, 9~16쪽, 전체 8쪽
• 주제분류: 의약학 > 한의학
• 파일형태: PDF
• 발행일자: 2015.12.30

영문 초록

Objectives : We developed new Yakchim M (MY) for activation of brain function and inhibition of inflammation with complex herbal extract including Gastrodiae Rhizoma, Cynanchi Wilfordii Radix, Polygalae Radix, Acori Graminei Rhizoma, Aucklandiae Radix, and Aquilariae Lignum and investigated the pharmacological activities and cell toxicity of MY. Methods : The anti-oxidant effect of MY was investigated by determining 2,2-diphenyl-1-picryl hydrazyl (DPPH) free radical scavenging activity. We investigated for the anti-inflammatory effect of MY, LPS-induced nitric oxide (NO) production in RAW 264.7 cells. Also We investigated cell toxicity of MY, cell viability of MY on RAW 264.7 cells using MTT assay. Results : MY showed dose dependent DPPH radical scavenging rate and inhibitory effect of LPS-induced nitric oxide (NO) production in RAW 264.7. and MY (1 mg/ml) did not show cell toxicity in the MTT assay. Conclusions : These results suggested that MY has anti-oxidant, and anti-inflammatory activities. However, more efficacy and safety studies are needed for the development of MY as a medicinal preparation on brain function improvement and anti-inflammation.

목차

Ⅰ. 서 론

Ⅱ. 재료 및 방법

Ⅲ. 연구결과

Ⅳ. 고 찰

Ⅴ. 결 론

참고문헌

키워드

M Yakchim anti-oxidant anti-inflammatory