동충하초 발효 불가사리의 발효 조건에 따른 항산화 및 항염증 효능 연구

• 영문명: Study of Fermentation Condition of Anti-oxidant and Anti-inflammatory Effects of Starfish Extract Fermented by Cordyceps militaris
• 발행기관: 임상약침학회
• 저자명: 임우현(Wu-Hyun Im) 임영훈(Young-Hoon Lim) 김연숙(Yon-Suk Kim) 박표잠(Pyo-Jam Park) 김학주(Hak-Ju Kim)
• 간행물 정보: 『임상약침학회학회지』대한면역약침학회지 제4권 제2호, 27~36쪽, 전체 10쪽
• 주제분류: 의약학 > 한의학
• 파일형태: PDF
• 발행일자: 2015.12.30

영문 초록

Objectives : The purpose of this study is the investigation of anti-oxidant and anti-inflammatory activities of starfish fermented extract. Methods : In this study, we investigated the anti-oxidant effect of starfish fermented extract through 1,1-Diphenyl-2- picrylhydrazyl (DPPH) radical-scavenging activity and the anti-inflammtory effect through inhibition of cyclooxygenase (COX) and nitric oxide (NO) production in lipopolysaccharide (LPS)-treated Raw 264.7 macrophages respectively. The starfish extract was fermented by Cordyceps militaris. Results : The starfish extract before fermentation showed only 10% DPPH radical scavenging activity, while fermented starfish extracts had 77.3% DPPH radical scavenging activity. In the case of anti-inflammatory, the extract had inhibition of COX-1 and COX-2. Also it decreased the production of NO in Raw 264.7 cells activated by LPS. Conclusions : The starfish fermented extract had anti-oxidant and anti-inflammatory effect and the efficacy increased by fermentation.

목차

Ⅰ. 서 론

Ⅱ. 재료 및 방법

Ⅲ. 연구결과

Ⅳ. 고 찰

Ⅴ. 결 론

Acknowledgments

참고문헌

키워드

Starfish Cordyceps militaris anti-oxidant anti-inflammatory