서부 경남지역 내인성 안내염의 임상양상과 예후

• 영문명: Clinical Characteristics and Prognosis of Endogenous Endophthalmitis in Western Gyeongsangnam-do
• 발행기관: 대한안과학회
• 저자명: 정지성(Ji-Seong Jeong) 신민호(Min Ho Shin) 서진석(Jin Seok Seo) 유웅선(Woong-Sun Yoo) 박종문(Jong Moon Park) 정인영(In Young Chung)
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume60,number9, 851~858쪽, 전체 8쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2019.09.30

영문 초록

Purpose: To investigate the clinical features and prognosis associated with endogenous endophthalmitis (EE) in western Gyeongsangnam-do over an 11-year period. Methods: This study was a retrospective review of the medical records of 24 patients (33 eyes) who presented with endogenous endophthalmitis at the Gyeongsang National University Hospital from 2007 to 2017. Results: The mean age of onset was 63.2 years, and 58.3% of the patients were men. Bilateral involvement was observed in nine patients (37.5%). Liver abscess (30.3%) and urinary tract infection (24.2%) were the most common extraocular sources of infection. Positive culture result was noted in 72.7% of the patients. The most common causative agents were gram-negative organisms (45.8%); the most commonly isolated microorganism was Klebsiella pneumoniae. Vitreous tapping and intravitreal antibiotic injection were performed in all patients; pars plana vitrectomy with intravitreal injection of antibiotics was performed in 12 eyes (36.4%). Enucleation and evisceration were performed in six eyes (18.2%). Initial visual acuity worse than hand motion was associated with a significantly worse visual outcome (p = 0.001). Conclusions: In our study, EE showed a poor visual prognosis, irrespective of treatment. Poor initial visual acuity was predictive of poor visual outcome. Liver abscess and urinary tract infections were common extraocular sources of EE and K. pneumoniae was the most common causative organism.

키워드

Endophthalmitis Klebsiella Prognosis Liver abscess