만성발암성 흡입독성시험 우선순위 물질 선정 연구

• 영문명: Prioritization of Chemicals for Chronic/Carcinogenic Inhalation Testing
• 발행기관: 한국환경보건학회
• 저자명: 임경택(Kyung-Taek Rim) 임철홍(Cheol-Hong Lim) 김현영(Hyeon-Yeong Kim) 차신우(Shin-Woo Cha) 허용(Yong-Heo) 윤진하(Jin-Ha Yoon) 김형아(Hyung-A Kim)
• 간행물 정보: 『한국환경보건학회지』제43권 제1호, 23~41쪽, 전체 19쪽
• 주제분류: 공학 > 환경공학
• 파일형태: PDF
• 발행일자: 2017.02.28

영문 초록

Objectives: In this study, we seek to perform a priority selection for test substances for chronic inhalation toxicity studies, including acute and subchronic inhalation toxicity studies, which are to be performed after the construction of a chronic/carcinogenicity inhalation toxicity study facility and enactment of pertinent legislation. Methods: Through this study, qualitative and quantitative priority evaluation of test substances according to acute, subchronic and chronic categories were respectively performed and priorities were suggested by expert group review, redundancy and other methods. Meanwhile, a draft on test substance selection criteria, procedures and methods referring to the National Toxicology Program (NTP) system was proposed. Results: This study selected priorities for candidate substances for chronic inhalation toxicity studies to be conducted from 2016. Conclusions: In the future, by assessing in advance the toxicological effects of chemicals to which workers can be potentially exposed in the workplace via long-term inhalation, expected health disturbances among workers will be reduced and it is anticipated that occupational disease induced by chemicals will be effectively prevented.

목차

I. 서 론

II. 연구 방법

III. 결 과

IV. 고 찰

V. 결 론

키워드

Carcinogenicity Chronic Inhalation Toxicity Selection Test substance