Pathological study of Korean native pregnant cows and fetuses experimentally vaccinated with Brucella abortus RB51 in heifers and challenged with Brucella abortus 2308 in pregnancy

• 발행기관: 한국예방수의학회
• 저자명: You-Chan Bae Gye-Hyeong Woo Ha-Young Kim Moon Her Dong-Hee Cho Suk-Chan Jung Jae-Ku Oem Jae-Won Byun Yi-Seok Joo O-Soo Lee Myoung-Heon Lee
• 간행물 정보: 『Korean Journal of Veterinary Public Health』Vol.36, No.3, 109~113쪽, 전체 5쪽
• 주제분류: 의약학 > 면역학
• 파일형태: PDF
• 발행일자: 2012.09.30

영문 초록

Bovine brucellosis causes abortion and infertility. The authors conducted this study in order to determine pathological lesions of Korean native cows and fetuses who received experimental vaccination with Brucella abortus RB51 and were challenged with Brucella abortus 2308. Gross and histopathological lesions in endometrium and placenta were observed in cows of the vaccinated group. Twenty-five percent of pregnant cattle in the vaccinated group showed endometritis and placentitis, which was three times lower, compared with the non-vaccinated group. The pathological lesions in the uterus and placenta in both groups were consistent with previous reports. Therefore, vaccination in heifers using Brucella abortus RB51 may not provide adequate protection against infection with Brucella abortus virulent strain.

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키워드

Brucella abortus RB51 Cattle Pathological Lesion