고식적인 라섹과 웨이브프론트 방식을 이용한 라섹 전후의 고위수차의 변화 비교

• 영문명: Comparison of Changes in Higher-order Aberrations between Conventional and Wavefront-guided LASEK
• 발행기관: 대한안과학회
• 저자명: 이상목 이민정 김미금 위원량 이진학,Sang Mok Lee, M.D.,, Min Joung Lee, M.D.,, Mee Kum Kim, M.D.,, Won Ryang Wee, M.D.,, Jin Hak Lee, M.D.,
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume48,number8, 1028~1035쪽, 전체 8쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2007.08.31

영문 초록

Purpose: To evaluate the postoperative higher-order aberrations (HOAs) and factors affecting postoperative changes in HOAs in eyes that underwent wavefront-guided LASEK (laser-assisted subepithelial keratectomy), compared with the eyes that underwent conventional LASEK. Methods: We reviewed the medical records of 221 patients who had undergone LASEK or wavefront guided LASEK with VISX WaveScan and VISX Star S4 eximer laser by a single surgeon (427 total eye operations). We matched 29 eyes of the LASEK and the wavefront LASEK groups (58 eyes total) according to the guideline: preoperative refractive power differences must be within 1 diopter and preoperative root-mean-square (RMS) of total HOAs differences must be within 0.01 ?m. Preoperative wavefront aberrations and two-months postoperative wavefront aberrations and associated factors were compared and analyzed. Results: Postoperative total HOAs, comas, and spherical aberrations increased significantly from 0.36±0.10 ?m to 0.49±0.16 ?m (p=.001), 0.21±0.09 ?m to 0.31±0.14 ?m (p=.003), and 0.03±0.10 ?m to 0.10±0.20 ?m (p=.043), respectively, in the conventional LASEK group. In the wavefront LASEK group, postoperative HOAs, comas, and spherical aberrations significantly increased from 0.36±0.10 μm to 0.46±0.14 μm (p=.004), 0.18±0.10 ?m to 0.29±0.14 ?m (p=.002), and 0.09±0.14 ?m to 0.19±0.14 ?m (p=.006), respectively. There were no significant differences in HOAs between the two groups. A strong negative correlation between preoperative total HOAs and a multiple of increase in total HOAs postoperatively was found, with the negative correlation being stronger in the wavefront-guided LASEK group (Pearson’s correlation coefficient =-0.697, p<.001) than in the LASEK group (Pearson’s correlation coefficient =-0.632, p<.001). Conclusions: There were no significant decreases in HOAs in the eyes that underwent wavefront-guided LASEK compared with the matched control eyes of patients that underwent conventional LASEK. Analyzing the tendency of a multiple of increase in total HOAs according to the preoperative HOAs, it suggests that the wavefront-guided LASEK may be more effective in suppressing an increase in total HOAs in the eyes with higher preoperative HOAs.

키워드

Case control study, Higher order aberrations, LASEK, Postoperative change, Wavefront