윌슨병 환자에서 다발성 섬유선종을 동반한 거대유방증 1예

• 영문명: Macromastia with Multiple Fibroadenomas in a Wilson's Disease Patient
• 발행기관: 대한내분비외과학회
• 저자명: 김훈혁 성기영 백종민 이도상 김욱 박일영 원종만 Hoon Hyuk Kim M.D. Gi Young Sung M.D. Jong Min Baek M.D. Do Sang Lee M.D. Wook Kim M.D. Il Young Park M.D. and Jong Man Won M.D.
• 간행물 정보: 『The Koreran journal of Endocrine Surgery』4권2호, 115~118쪽, 전체 4쪽
• 주제분류: 의약학 > 면역학
• 파일형태: PDF
• 발행일자: 2004.12.30

영문 초록

Wilson's disease is an autosomal recessive disorder of copper metabolism in individuals with mutant ATP7B genes. Impairment of normal excretion of hepatic copper results in toxic accumulation of the metal in liver, brain and other organs. Clinical manifestations include hepatic, neurologic or psychiatric disturbances. Penicillamine, as a chelator of copper, is the drug of choice in the treatment of Wilson's disease but after treatment of penicillamine, granulocytopenia, thrombocytopenia, the nephrotic syndrome, Goodpasture's syndrome, pemphigus vulgaris or pleural effusion may supervene. We report a case of macromastia with multiple fibroadenomas in a patient who was treated with penicillamine for Wilson's disease. (Korean J Endocrine Surg 2004;4:115-118)

키워드

윌슨병, 페니실라민, 거대유방증,Wilson's disease, Penicillamine, Macromastia