기관식도 침범이 있는 분화 갑상선암의 치료

• 영문명: Treatment of Well-differentiated Thyroid Carcinoma with Aerodigestive Tract Invasion
• 발행기관: 대한내분비외과학회
• 저자명: 하정훈 정은정 노동환 권성근 성명훈 김광현 Jeong-Hun Hah M.D. Eun-jung Jung M.D. Dong Hwan Roh M.D. Seong Keun Kwon M.D. Myung-Whun Sung M.D. and Kwang Hyun Kim M.D.
• 간행물 정보: 『The Koreran journal of Endocrine Surgery』4권2호, 101~105쪽, 전체 5쪽
• 주제분류: 의약학 > 면역학
• 파일형태: PDF
• 발행일자: 2004.12.30

영문 초록

Purpose: Well differentiated thyroid carcinomas are mostly curable diseases. Invasion of aerodigestive tract by thyroid carcinoma is rare. However, it is considered as a poor prognostic indicator of survival. Some studies showed that local invasion of thyroid carcinoma was the cause of death in many patients. Therefore, adequate local control of the tumor is critical to avoid the mortality as well as the morbidity of the disease. To find proper and adequate treatment modality of locally invasive thyroid carcinoma, we evaluated treatment modalities and outcomes in the patients with thyroid carcinoma with invasion of aerodigestive tract. Methods: Forty patients with thyroid carcinoma invading aerodigestive tract who were treated from July 1989 through July 2002 were reviewed retrospectively. Results: Direct intraluminal invasion of the thyroid carcinoma requires definitive resection of the aerodigestive tract. In case that the extent of tumor was thought to be limited to perichondrium or extraluminal invasion, tracheal shaving procedure was performed. Five-year and 10-year local control rates were 81.6% and 57.4%, respectively. Disease-specific survival rates of 5-year and 10-year were 90.1% and 81.1%, respectively. Conclusion: For the successful treatment of invasive thyroid carcinoma, the resection of the functional structures or the aerodigestive tract should be determined prudently according to the presence of the intraluminal invasion. (Korean J Endocrine Surg 2004;4:101-105)

키워드

갑상선암, 기관식도 침범,Thyroid carcinoa, Aerodigestive tract invasion