부갑상선 증식증의 수술적 치료 경험

• 영문명: The Experience of Surgical Management for Parathyroid Hyperplasia
• 발행기관: 대한내분비외과학회
• 저자명: 정파종 이국현 김한준 Pa Jong Jung M.D. Kuk Hyun Lee M.D. and Han Joon Kim M.D.
• 간행물 정보: 『The Koreran journal of Endocrine Surgery』3권1호, 26~31쪽, 전체 6쪽
• 주제분류: 의약학 > 면역학
• 파일형태: PDF
• 발행일자: 2003.04.30

영문 초록

Parathyroid hyperplasia is a pathologic finding that can be found in hyperparathyroidism. Unlike parathyroid adenoma, treatment of parathyroid hyperplasia is still quite controversial. In addition, the relative merits of two alternative surgical approaches-subtotal parathyroidectomy versus total parathyroidectomy with autotransplantation have not been clearyly elucidated. The records of 10 patients who had parathyroid hyperplaisa and who underwent parathyroid surgery at the Department of Surgery, Hanyang University Hospital, between April 1992 and April 2003 were retrospectively reviewed. The 10 patients were comprised of 3 males and 7 females. The age distribution was between 29 and 73 years. The presenting clinical manifestations were associated with bone pain in 8 patients, muscle weakness in 4, headache in 4, gastrointestinal symptoms in 3, renal symptoms in 3 and psychologic symptoms in 2. The serum parathyroid hormone level was elevated in all patients. The serum alkaline phosphatase level was elevated in seven among the ten patients. Histopathologic findings revealed chief cell hyperplasia in all patients. Postoperative transient hypocalcemia occurred in 5 patients and they were supplied with oral calcium and calcitriol for several months. There were no major complications. The results indicate that a subtotal parathyroidectomy can be performed without mortality or morbidity and provides good control of primary parathyroid hyperplasia, A total prathyroidectomy with autotransplantation can be performed without mortality or morbidity and provides good contril of secondary and tertiary parathyroid hyperplaisa. (Korean J Endocrine Surg 2003; 3:26-31)

키워드

부갑상선증식증, 부갑상선 기능항진, 부갑상선 아전절제술, 부갑상선 전절제술, 부갑상선 자가이식술,Parathyroid hyperplasia, Hyperparathyroidism, Subtotal parathyroidectomy, Total prathyroidectomy, Parathyroid autotransplantation