Application of Near-Infrared Autofluorescence Imaging Technology in Assisting Adrenal Gland Localization During Adrenal Tumor Resection: A Case Report and Literature Review

• 발행기관: 대한내분비외과학회
• 저자명: Chang Cai Xiao Xiao DianXin Zhou YiLing Li Xiezhao Li Zifeng Luo Yifan Liu Song Wang
• 간행물 정보: 『The Koreran journal of Endocrine Surgery』25권3호, 101~108쪽, 전체 8쪽
• 주제분류: 의약학 > 면역학
• 파일형태: PDF
• 발행일자: 2025.09.30

국문 초록

The adrenal gland is a crucial endocrine organ, and adrenal tumors, mostly benign, often require surgical treatment. However, intraoperative localization of the adrenal gland is challenging due to its anatomical features. Laparoscopic surgery is widely used, but current laparoscopes lack real - time adrenal navigation. Near-infrared autofluorescence imaging (NIRAF) is a non-invasive technology that shows potential in adrenal localization, with limited reports globally and none in China. A 37-year-old female with a left adrenal nodule underwent retroperitoneoscopic left adrenal tumor resection. NIRAF technology, combined with laparoscopy, was used. The equipment had white light and near-infrared light modes. In the near-infrared light mode, the adrenal gland's autofluorescence was detected for intraoperative identification. Intraoperative NIRAF laparoscopy showed high-intensity fluorescence of the left adrenal tissue, clearly differentiating it from surrounding tissues. The surgery was completed within one hour without damage to surrounding organs. Post-operative monitoring of indicators such as blood pressure, aldosterone, adrenocorticotropic hormone, and white blood cell count was carried out. NIRAF technology has advantages in adrenal tumor resection, like improving surgical efficiency, reducing tissue manipulation, and lowering bleeding and infection risks. However, it has limitations such as weak light penetration and limited research. Further studies are needed to clarify its autofluorescence mechanism and evaluate its long-term effects.

목차

INTRODUCTION

CASE REPORT

DISCUSSION

ACKNOWLEDGMENTS

REFERENCES

키워드

Adrenal gland Adrenal gland neoplasms Near-infrared fluorescence imaging Autofluorescence