인삼이 신경 및 근육 세포에 미치는 영향에 대한 연구

• 영문명: Studies on the Effect of Ginseng Extract on Chick Embryonic Nerve and Muscle Cells
• 발행기관: 대한약학회
• 저자명: 김영중(Young Choong Kim) 김은경(Eun Kyung Kim)
• 간행물 정보: 『약학회지』제24권 제3&4호 (1980년), 143~150쪽, 전체 8쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1980.12.30

영문 초록

The effect of ginseng saponin on chick embryonic dorsal root ganglia organ culture and brain, spinal cord, muscle dissociation cultures was studied. The fiber outgrowth in explanted chick embryonic dorsal root ganglia was markedly induced by water and alcohol extracts of ginseng, total ginseng saponin, protopanaxadiol and protopanaxatriol glycosides as well as ginsenosides Rb1, Rd, R0+Ra+Rb1, and Rb2+Rc+Re mixtures. The life span of the cultured chick embryonic dorsal root ganglia and potentiation of nerve cell density were also observed with all of these ginseng saponins. The effect of ginseng saponin on chick embryonic dorsal root ganglia organ culture was more marked in the absence of the chick embryonic extract which was known to contain nerve growth factor-like material in the culture media. However, the ginseng saponin did not influence the cultured central nervous system such as brain and spinal cord cells and cultured skeletal muscle cells with respect to the morphological changes, maturation and life span of these cells.