질경이 추출물의 항산화 효과 및 각질세포 보호효과

• 영문명: Antioxidant effects of Plantago asiatica and protective effects on Human HaCaT Keratinocyte
• 발행기관: 한국인체미용예술학회
• 저자명: 유민정(Min Jeong Ryu) 이숙영(Sook Young Lee)
• 간행물 정보: 『한국인체미용예술학회지』한국인체미용예술학회지 제11권 제3호, 15~25쪽, 전체 11쪽
• 주제분류: 예술체육 > 예술일반
• 파일형태: PDF
• 발행일자: 2010.09.30

영문 초록

This study was carried out to investigate antioxidative effects of Plantago asiatica and protective effects on Human HaCaT keratinocyte. The extracts were prepared by ethanol extraction method. The antioxidant activities of extracts was used the method of DPPH radical, total phenolics and flavonoids contents. In our results, treatment with Plantago asiatica did not show cytotoxicity on HaCaT keratinocyte beneath the concentration of 20, 50 ㎍/㎖. The DPPH radical scavenging activity of the aerial part of Plantago asiatica showed a considerable IC50 value (170.4 ㎍/㎖) and it was higher than that of BHT standard oxidant. The contents of total phenolics (174.0 ㎍/㎖) and flavonoids (130.9 ㎍/㎖). Plantago asiatica showde protective effect against cell death of HaCaT cell induced by hydrogen peroxide, rotenone, paraquat significantly. These results suggested that Plantago asiatica may have antioxidantic action in human skin and also suggest the possibility as cosmetic material.

목차

Ⅰ. 서론

Ⅱ. 재료 및 방법

Ⅲ. 결과 및 고찰

Ⅳ. 결론

키워드

항산화 각질세포 폴리페놀 플라보노이드 Antioxidative HaCaT keratinocyte polyphenol flavonoid