직장암의 방사선 치료결과 및 실패양상

• 영문명: The Result and Failure after Adjuvant Postoperative Irradiation in Carcinoma of Recum
• 발행기관: 대한방사선종양학회
• 저자명: 김철용 Chul-Yong Kim 최명선 Myung-Sun Choi
• 간행물 정보: 『대한방사선종양학회지』제11권 제1호, 133~141쪽, 전체 9쪽
• 주제분류: 의약학 > 종양학
• 파일형태: PDF
• 발행일자: 1993.06.30

영문 초록

From Jan. 1982 to Dec. 1990, 77 patients with rectal cancer were treated with curative surgical resection followed by postoperative adjuvant irradiation alone or combined with chemotherapy at the Department of Radiation Oncology, Korea University Hospital (KUH). Fifty-four (54/77, 70.1%) patients underwent abdominoperineal resection, 20 (20/77, 26%) patients underwent low anterior resection, and 3 (3/77, 3.9%) patients had wide excision only. Thirty-nine (39/77, 50.5%) received sequential chemotherapy (2 cycles to 12 cycles). The 5-year survival rate for the entire group was 43%: 78.2% in B2+B3, 39.4% in stage C1+C2+C3. Survival rates decreased with increasing penetration of the bowel wall by tumor and the presence of regional lymph node metastasis. those patients survival who underwent an abdominoperineal resection also experienced a significant decrease in compared to low anterior resection (23.1% vs. 63.8% in 5-year survival, p<0.05). Local failure occurred in 15 (19.5%) out of the 77 patients overall, 1 (5.3%) of 19 in stage ㅠ2+B3, and 14 (24.1%) of 58 in stage C1+C2+C3. presacral area was most common site of local failufre (8/17, 47.1%). Distant faliure occurred in 13(16.9%) of 77 patients. The most frequent site of distant failure was the lung followed by the liver, the bone, and the brain. Combined locoregional and distant failure occurred in 2 (2.6%) of 77 patients. pathological confirmation of perirectal fat and/or regional lymph node involvement resulted in a singificant decrease in survival and local control.

목차

abstract

서론

대상 및 방법

결과

고찰

결론

REFERENCES

키워드

Rectal cancer Postoperative adjuvant irradiation.