수술불능 및 재발성 직장암에 대한 중성자선 치료

• 영문명: Neutron Therapy of Unresectable and Recurrent Rectal Cancer
• 발행기관: 대한방사선종양학회
• 저자명: 류성렬 (Seong Yul Yoo) 고경환 (Kyoung Hwan Koh) 조철구 (Chul Koo Cho) 박우윤 (Woo Yun Park) 윤형근 (Hyong Geun Yun) 심재원 (Jae Won Shim)
• 간행물 정보: 『대한방사선종양학회지』제11권 제1호, 127~132쪽, 전체 6쪽
• 주제분류: 의약학 > 종양학
• 파일형태: PDF
• 발행일자: 1993.06.30

영문 초록

Total of 53 patients of unresectable and recurrent rectal cancer treated with neutron beam during the period from Oct. 1987 to Apr. 1992 were analyzed. Dose fractionation for the neutron only group was 1.5 Gy per fraction, 3 fraction per week, 21 Gy/4¹/₂ wks for 42 patients out of 53 (76%). Neutron only but modified fractionation schedule (10% more or less of total dose) was applied for 9 patients, and mixed beam (neutron boost) was for 4 patients. Complete tumor response was obtained in 40 patients (76% response rate). Local control rate was 28 out of 53 (53%). Statistically significant better prognostic factors for local control were age below 49 years old (15/22, 68%) than above 50 years old (13.31, 42%), male (20/32, 63%) than female (8/21, 38%), tumor size less than 5 cm and non-metastatic (16/24, 67%) than size more than 5 cm or metastatic (12/29, 41%). Major complication had developed in 7 patients (13%). Two year overall survival rate by Kaplan-Meier method was 30%, but it was rised to, 47% when the tumor was less than 5 cm non-metastatic.

목차

abstract

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대상 및 방법

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REFERENCES

키워드

Rectal cancer Neutron therapy