율무 부탄올 분획의 항산화 효과

• 영문명: Antioxidant Effects of n-butanol Fraction of Coix Seed
• 발행기관: 충북대학교 생활과학연구소
• 저자명: 윤혜지(Hye Ji Yoon) 이화진(Hwa Jin Lee)
• 간행물 정보: 『생활과학연구논총』생활과학연구논총 제25권 제2호, 77~86쪽, 전체 10쪽
• 주제분류: 자연과학 > 생활/식품과학
• 파일형태: PDF
• 발행일자: 2021.08.31

영문 초록

To evaluate the antioxidant activity of coix seed (Coix lacryma-jobi L. var. mayuen Stapf), w e prepared the methanolic extract of coix seed and, subsequently, solvent polarity based frac tionation such as n-hexane, ethyl acetate, and n-butanol fraction, and then we determined th e content of the total polyphenols. The n-butanol fraction of coix seed (CLBu) displayed a hi gh level of polyphenols. And then we examined whether CLBu scavenges DPPH and ABTS fre e radicals, and possesses reducing power. CLBu demonstrated potent DPPH and ABTS free ra dical scavenging effects and a high level of reducing power. In addition, we investigated whe ther CLBu could inhibit the nitric oxide (NO) production in lipopolysaccharide (LPS)-activated RAW264.7 macrophages. The simultaneous cell viabilities showed CLBu protected the cell da mages from a high level of LPS-induced NO in RAW264.7 cells. These results suggested that CLBu may be a good source of antioxidant functional foods.

목차

I. 서 론

II. 연구방법

III. 결과 및 논의

IV. 결론 및 제언

V. 참고문헌

키워드

Coix seed Coix Lachryma-jobi L. var. mayuen Stapf Antioxidant Radical Scavenging Polyphenol